Editorial: Engadget on Microsoft's new Surface tablet line

Microsoft has unveiled its new Surface, a reborn brand that now lives as two products. It was a showy event with a strong conclusion: at the unification of software and hardware lies great things. Microsoft has found that greatness with the Xbox 360. Can it do so again with a new series of tablets? Here's what we think.

Continue reading Editorial: Engadget on Microsoft's new Surface tablet line

Editorial: Engadget on Microsoft's new Surface tablet line originally appeared on Engadget on Tue, 19 Jun 2012 10:09:00 EDT. Please see our terms for use of feeds.

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Annals of Internal Medicine tip sheet for June 19, 2012, online issue

Public release date: 18-Jun-2012
[ | E-mail | Share ]

Contact: Abbey Anderson
aanderson@acponline.org
215-351-2656
American College of Physicians

Embargoed news for Annals of Internal Medicine

1. Hospitalization Often Catastrophic for Alzheimer Patients

Hospitalization of patients with Alzheimer disease (AD) often leads to complications such as delirium, loss of independence, institutionalization, and death. Researchers theorized that AD patients who suffer an episode of delirium during hospitalization are at increased risk for adverse outcomes. In a prospective study, researchers reviewed 15 years of medical records for a cohort of 771 patients aged 65 or older with a clinical diagnosis of AD to determine which patients, and under what circumstances, had hospitalization, delirium, death, and/or institutionalization. The records showed that 48 percent of the study patients were hospitalized and 25 percent developed delirium during their stay. While hospitalized patients without delirium had a substantially increased risk for death and institutionalization, those with delirium had an even higher risk. Further research is needed to understand whether delirium is only a signal that precedes decline for patients with AD or if preventing it can reduce adverse outcomes.

---

2. Osteoarthritis Treatment, Flavocoxid, Linked to Significant Liver Injury

Osteoarthritis is a common and potentially debilitating joint disorder caused by aging and regular wear and tear. Painkillers prescribed for osteoarthritis offer limited pain relief and are associated with adverse events. Flavocoxid is a proprietary medical food that is marketed to treat osteoarthritis. A medical food is a specially formulated supplement used to manage diseases with specific nutritional requirements that cannot be met through normal diet. Unlike drug treatments, medical foods can be marketed without clinical trials proving safety and efficacy. In this case series, the authors describe characteristics of patients with acute liver injury that is suspected to have been caused by flavocoxid. Among 877 patients enrolled in the Drug-Induced Liver Injury Network Prospective Study, four developed symptoms and signs of liver injury within three months after initiating flavocoxid. The four patients all females between the ages of 57 and 68 were evaluated to determine the likely cause of their liver injury. The researchers concluded that flavocoxid was very likely to be the cause in three patients and was possibly the cause in one patient. For all four patients, the liver injury resolved within weeks of cessation. According to the authors of an accompanying editorial, patients often consider medical foods and food supplements to be "natural", so they may not disclose use of medical foods with their physician. The editorialists caution that physicians should discourage their patients from using any kind of medical food or supplement until policies related to marketing are changed to include safety and efficacy trials.

---

3. Patients with Alcoholic Cirrhosis Probably Won't Die from Liver Cancer

Screening These Patients for Liver Cancer Not Likely to Save Lives, Unlikely to be Cost-effective

Patients with alcoholic cirrhosis have an increased risk for liver cancer. It has been suggested that screening for liver cancer in this population may save lives, yet no randomized trials have examined the effect of liver cancer screening on total mortality or liver cancer-related mortality in patients with alcoholic cirrhosis. Researchers in Denmark studied a nationwide registry of patients hospitalized with a first-time diagnosis of alcoholic cirrhosis from 1993 to 2005. Among 8,482 patients, 169 developed liver cancer, and 5,734 died, 151 of whom had liver cancer. The incidence and mortality of liver cancer was no greater in the alcoholic cirrhosis patients than those in the nationwide cohort. The researchers conclude that screening for liver cancer in alcoholic cirrhosis patients would not decrease the high mortality in this population, nor would it be cost-effective.

###

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?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 18-Jun-2012
[ | E-mail | Share ]

Contact: Abbey Anderson
aanderson@acponline.org
215-351-2656
American College of Physicians

Embargoed news for Annals of Internal Medicine

1. Hospitalization Often Catastrophic for Alzheimer Patients

Hospitalization of patients with Alzheimer disease (AD) often leads to complications such as delirium, loss of independence, institutionalization, and death. Researchers theorized that AD patients who suffer an episode of delirium during hospitalization are at increased risk for adverse outcomes. In a prospective study, researchers reviewed 15 years of medical records for a cohort of 771 patients aged 65 or older with a clinical diagnosis of AD to determine which patients, and under what circumstances, had hospitalization, delirium, death, and/or institutionalization. The records showed that 48 percent of the study patients were hospitalized and 25 percent developed delirium during their stay. While hospitalized patients without delirium had a substantially increased risk for death and institutionalization, those with delirium had an even higher risk. Further research is needed to understand whether delirium is only a signal that precedes decline for patients with AD or if preventing it can reduce adverse outcomes.

---

2. Osteoarthritis Treatment, Flavocoxid, Linked to Significant Liver Injury

Osteoarthritis is a common and potentially debilitating joint disorder caused by aging and regular wear and tear. Painkillers prescribed for osteoarthritis offer limited pain relief and are associated with adverse events. Flavocoxid is a proprietary medical food that is marketed to treat osteoarthritis. A medical food is a specially formulated supplement used to manage diseases with specific nutritional requirements that cannot be met through normal diet. Unlike drug treatments, medical foods can be marketed without clinical trials proving safety and efficacy. In this case series, the authors describe characteristics of patients with acute liver injury that is suspected to have been caused by flavocoxid. Among 877 patients enrolled in the Drug-Induced Liver Injury Network Prospective Study, four developed symptoms and signs of liver injury within three months after initiating flavocoxid. The four patients all females between the ages of 57 and 68 were evaluated to determine the likely cause of their liver injury. The researchers concluded that flavocoxid was very likely to be the cause in three patients and was possibly the cause in one patient. For all four patients, the liver injury resolved within weeks of cessation. According to the authors of an accompanying editorial, patients often consider medical foods and food supplements to be "natural", so they may not disclose use of medical foods with their physician. The editorialists caution that physicians should discourage their patients from using any kind of medical food or supplement until policies related to marketing are changed to include safety and efficacy trials.

---

3. Patients with Alcoholic Cirrhosis Probably Won't Die from Liver Cancer

Screening These Patients for Liver Cancer Not Likely to Save Lives, Unlikely to be Cost-effective

Patients with alcoholic cirrhosis have an increased risk for liver cancer. It has been suggested that screening for liver cancer in this population may save lives, yet no randomized trials have examined the effect of liver cancer screening on total mortality or liver cancer-related mortality in patients with alcoholic cirrhosis. Researchers in Denmark studied a nationwide registry of patients hospitalized with a first-time diagnosis of alcoholic cirrhosis from 1993 to 2005. Among 8,482 patients, 169 developed liver cancer, and 5,734 died, 151 of whom had liver cancer. The incidence and mortality of liver cancer was no greater in the alcoholic cirrhosis patients than those in the nationwide cohort. The researchers conclude that screening for liver cancer in alcoholic cirrhosis patients would not decrease the high mortality in this population, nor would it be cost-effective.

###

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

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Myanmar boat people swap violence for desperation

GOLAR PARA, Bangladesh (Reuters) - At first, the boat bobbing in the water in the middle of the night appeared to be empty. But when Bangladeshi villagers took a closer look, they found a baby too weak to cry, a refugee from marauding mobs in Myanmar apparently abandoned by her family.

The cleft-lipped infant, just weeks old, is among hundreds of Rohingya Muslims who fled this month's sectarian violence in Myanmar's western state of Rakhine, packing themselves into rough wooden boats and heading for the shores of neighboring Bangladesh.

No one knows how many made it ashore. Bangladesh has ordered its border guards to push the boats back, determined that - with at least quarter of a million "illegal migrants" already here - there must be no more.

The baby, named Fatima by the family that has taken her in, is out of the danger that she and her family faced in Myanmar, but she joins a throng of stateless people in southeast Bangladesh who - for the most part - lead desperate lives of squalor, deprivation and discrimination.

Among them is Mohammad Kamal, a young religious leader from Rakhine's Maungdaw district, where ferocious violence erupted on June 9 between Rohingyas and ethnic Rakhine Buddhists and spread across the state. He escaped to Bangladesh in 2006 after his brother and others were jailed in a crackdown on Muslim clerics.

Kamal, now 28, settled in a makeshift "unregistered" camp, where - along with some 20,000 others - he is not recognized as a refugee and where even international aid agencies have to work under the radar because Bangladesh has not granted them legal status.

"I went out for a walk one day last year and was arrested because I had no documents," said Kamal, pulling up a trouser leg to show a line of angry sores that broke out during the following nine months he spent in jail.

Behind him, naked children play in a muddy pool and the rickety dwellings of an overcrowded shanty town - his camp - rise up, lashed by monsoon rains.

In 2010, the authorities forcibly evicted thousands from a makeshift camp. The medical charity Medecins Sans Frontieres recounted at the time that some Rohingyas had been thrown into the Naf River and told to swim the 3 km (2 miles) back to Myanmar, and the organization said it had treated many for beatings, machete wounds and even rape.

"A DESPERATE LIFE"

Craig Sanders, the U.N. High Commissioner for Refugees' representative in Dhaka, said that although Bangladesh has disowned the Rohingyas - dubbing them illegal economic migrants - it has shown "tremendous generosity over many years".

Rohingyas first came in large numbers to the South Asian nation in 1973, and over the years gained a reputation for drug-smuggling, gun-running and human trafficking.

A sudden flood of more than quarter of a million arrived in 1991-92 after a spasm of repression by the security forces in military-ruled Myanmar. Those that remain from that wave, now numbering some 30,000, live in two official camps where the U.N. provides everything from shelter and water supply to healthcare and schooling.

But at least 200,000 others - probably many more - have settled on the Bangladesh side of the 200-km (125-mile) border, mingling with the population where they struggle to find employment or squeezing into unofficial camps.

It is these "unregistered" Rohingyas who are most vulnerable.

"It's an extremely desperate life for these people," said one worker for a humanitarian group that provides assistance illegally at one camp, asking not to be named. "They have been here for such a long time and there is no prospect of change."

UNHCR's Sanders has crossed swords with the government in recent days over its decision to turn back the boatloads of traumatized Rohingyas.

"Bangladesh, one more time, is being urged to step forward to deal with a situation that is not of their making," he said. "We are not trying to push them into a corner on this issue, but there is a question of fair and right treatment here."

BANGLADESH SAYS "NO MORE"

There have been sketchy and conflicting reports of the communal violence that erupted in Rakhine, but scores are feared dead after widespread torching of houses by both sides.

Abdus Salam, one of 10 Rohingyas who reached Bangladesh and are now hiding in a coastal village to avoid arrest, told Reuters last week: "The Rakhine torched our houses, killed our relatives, assaulted our women. They were killing Muslims. When we protested, the government forces also shot our people dead. Then we started fleeing."

Muhammad Zamir, Dhaka's chief information commissioner, maintains that the authorities have treated the boat people humanely, providing those they turn away with water, medicines and fuel for the journey back, assisting a woman who gave birth on arrival and treating those with gunshot wounds in hospital.

"We want to help the refugees, they have rights," Zamir told Reuters in the coastal town of Cox's Bazar, a bumpy three-hour drive from the shores where Rohingyas are being pushed back.

"But we can only look after them to a point. We really can't handle any more."

He argues that, as a densely populated and poverty-plagued country of 150 million, Bangladesh has played its part. Now, as democracy stirs in Myanmar, it is time for its neighbor to address the root causes of the chronic exodus of Rohingyas, and for the international community to put pressure on it to do so.

SILENT CRISIS

There has been some dismay in this part of Bangladesh at the hard line taken by the government on the new arrivals. The populations share the same ethnicity, religion and dialect, and they are so close that if you call a Rohingya on a mobile phone in Myanmar it is likely to be a Bangladesh number.

Yet the plight of those already here gets little attention.

A report by U.S.-based rights group Refugees International last year described a "silent crisis" of abuse, starvation and detention faced by stateless Rohingyas in Bangladesh.

According to UNHCR, a 2011 survey in the two official camps found that 17 percent of children between six months and six years were suffering from acute malnutrition, higher than the emergency threshold set by the World Health Organisation. In the makeshift camps, malnutrition rates are even higher.

"It's a hopeless situation," said the aid worker. "You treat the children who are sick, and then they fall ill again because they are not getting the right food."

For now at least, tiny Fatima is safe. She has been taken in by a fisherman and his wife who already have four sons and two daughters. But an uncertain future awaits her, stateless in the land of her refuge.

(Editing by Nick Macfie)

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Where To Find The Best Girls Softball Portland Classes Online

Learning a new sport or perfecting a sport you love can be a tough task to complete sometimes, but with the right training and assistance you can get there. People always say if you really want to succeed you will, but having the right coaching and instruction is key to achieving your goals quicker and more effectively. In every sport there are low quality instructors and high quality instructors, its up to you to find the most highest standard coaching that you can afford so that you can develop and progress in a timely fashion. You have to ask yourself just how good you want to get and what you want to get out of the sport, then you'll know just how seriously your taking it. One type of sport that's very popular in the Portland area is softball. Softball has been around for years and is very similar to baseball, many women and girls wish to get involved in softball but they're looking for the right environment, atmosphere and instructor to take them where they wish to go with it.

Having the right instructor is key to being successful and well trained in softball, you must be taught all the proper techniques and methods so that you can progress and evolve effectively and professionally in the sport. Without using a decent softball instructor you will find it very difficult to progress and get better, this is a sad truth that's seen in all sports with girls and boys as they just aren't taught in a way that resonates with them, therefore they don't enjoy the sport and they give it up. You must be taught on a level that you understand and can implement, without being taught in the right manner it will be very tough for you to develop skills and attributes in softball, finding the right teacher is essential.

A lot of people prefer to learn individually with an instructor as it allows them to have one on one personalized teaching, people are able to ask questions and get direct answers and solutions to their questions from their instructor. This is a very effective and professional way to learn softball and there are professional Girls Softball Portland individual classes that take place each and every day. If you want to perfect or learn the sport of softball then individual classes and instructions are definitely going to be the quickest most effective way to get you off the ground with your training, as long as you put in the practice and do what your trainer tells you to, you will be developing quality skills in softball quicker than you ever imagined you could. People underestimate the power of individual classes but even a few sessions a month or so with one instructor and yourself can make all the difference, whether you just want to perfect your swing or fielding you can do so with the aid of a personalized softball lesson. Book up an individual softball class today to perfect or learn the sport of softball in Portland.

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Concrete Contractor Abbotsford, bc - Choose Concrete Contractor in ...

You had been waiting long enough for the construction of the pool in your backyard where you had just dreamt to spend lazy afternoons in the cool water or have a great family time with some neatly arranged deck chairs by the pool while enjoying the fresh air. But when it actually took place, there was nothing more than disappointment on your face. The laying of the concrete has not been good and it has already started to show cracks on the surface. What a disaster and dreadful end to a surprise most awaited. Who is to blame for this? You or the contractor who has handled the job? Partially both. As the client, it was your responsibility to look for an experienced concrete contractor in Abbotsford, bc rather than passing the job on to some amateur.

Laying concrete is a tough job and there are very few good concrete contractors in Abbotsford, bc who can handle the job efficiently. Not only knowledge of laying the concrete but the art to handle different types of decorative concrete, structural concrete is also important. Moreover, the company with years of expertise in dealing with concrete should also have the right human resource and equipment to give shape to any concrete project that they undertake. What is crucial therefore is to opt for a concrete contractor who offers a range of services starting right from preparation to demolition and sealing.

A good concrete contractor in Abbotsford bc, knows the importance of laying down the perfect base. The initial stages of concrete laying is very crucial for its longevity. It requires a steady hand, clear concepts and ideas and the right tools to carry out the job flawlessly. Concrete contractors should be equipped with compactors for grading, leveling, compacting of the gravel base in preparation for forming and concrete placing.

Once the preparation work is handled, the contractor should also be able to carry out any kind of demolition work that is required. Any experienced concrete contractor in Abbotsfod bc, will be well equipped with sledge hammers, jack hammers, hydraulic breakers for mini-bobcats to large bobcan and mini-hoe to suit large areas as well as small or hard to reach places.

Next is the crucial step of laying or placing the concrete. If you are working with a good contractor you will realize the difference from the finished work. A concrete contractor who has had hands on experience will have power and hand tools to tackle concrete placement needs including power screed, laser levels, string lines and aluminum screeds for critical slopes and levels.

The last part or the finishing touch is laid down by sealing. Any good concrete contractor in Abbotsford, bc who has worked with concrete before will know the use of different kind of base sealers which are helpful in protecting and beautifying various kinds and finishes of concrete. To top it all, the contractor will also carry out an acid wash or pressure wash the concrete to clean prior to sealing.

For a long living concrete, it is therefore vital that the contractor who handles it knows the nature of it. A strong hand is what is required for shaping decorative and structural concrete at its best.

Keywords: Concrete Contractor Abbotsford, bc, decorative concrete Abbotsford, bc, structural concrete Abbotsford, bc

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Romney jokes with reporters on bus tour

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Bill Clinton: Mitt Romney Would Be 'Calamitous for Our Country'

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